From: Genetics and genomics of radiotherapy toxicity: towards prediction
Study population | Assay* | Heritability (%) | Reference |
---|---|---|---|
16 Radiosensitive breast cancer survivors and 37 first-degree relatives, 4 breast cancer survivors with normal radiosensitivity and 15 first-degree relatives | G2 | 82 | [41] |
23 Cancer survivors, 29 partners, 38 offspring, 27 controls | G2 | 67 | [76] |
148 Monozygotic and 57 dizygotic twin pairs; 50 siblings | Apoptosis | 63 | [77] |
199 Father, mother, offspring trios | Apoptosis | 61 | [78] |
38 Dizygotic and 16 monozygotic twin pairs | Apoptosis; cell cycle delay | 68; 59 | [40] |
29 Cancer survivors, 29 partners, 53 offspring | G2 | 58 to 78 | [79] |
39 Monozygotic and 10 dizygotic twin pairs | MN | 68 | [42] |