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Table 6 Prevalence of grayzone and premutation alleles in females and males across ethnic groups

From: FMR1 CGG allele size and prevalence ascertained through newborn screening in the United States

  

Overall

White

Black

Hispanic

Asian

Other

Unknown

  

Group* N = 14,179

N = 4,161

N = 3069

N = 3493

N = 796

N = 1286

N = 1374

Females (N)

 

6,889

2,014

1,508

1,709

368

614

676

Normal (count)

 

6,751

1969

1,479

1,677

360

601

665

   Gray

Count (rate)

105 (1:66)

35 (1:58)

20 (1:75)

29 (1:59)

5 (1:74)

8 (1:77)

8 (1:84)

 

(95% CI**) Gray

1:80-1:54

1:82-1:42

1:123-1:49

1:88-1:41

1:226-1:32

1:177-1:39

1:195-1:43

   Premutation

Count (rate)

33 (1:209)

10 (1:201)

9 (1:168)

3 (1:570)

3 (1:123)

5 (1:123)

3 (1:225)

 

(95% CI) Pre

1:303-1:149

1:420-1:110

1:366-1:89

1:2761-1:195

1:594-1:42

1:377-1:53

1:1092-1:77

Males (N)

 

7,290

2,147

1,561

1,784

428

672

698

Normal (count)

 

7,208

2,106

1,548

1,772

427

662

693

   Gray

Count (rate)

65 (1:112)

35 (1:61)

11 (1:142)

9 (1:198)

0 (N/A)

6 (1:112)

4 (1:174)

 

(95% CI) Gray

1:145-1:88

1:88-1:44

1:284-1:80

1:433-1:105

N/A

1:305-1:52

1:640-1:68

   Premutation

Count (rate)

17 (1:429)

6 (1:358)

2 (1:780)

3 (1:595)

1 (1:428)

4 (1:168)

1 (1:698)

 

(95% CI) Pre

1:736-1:268

1:974-1:165

1:6443-1:216

1:2882-1:204

1:16906-1:77

1:616-1:66

1:27570-1:126

  1. Group* refers to the total number of males and females for all ethnicities. CI** refers to Confidence Interval.