Figure 1From: Transcriptome-wide signatures of tumor stage in kidney renal clear cell carcinoma: connecting copy number variation, methylation and transcription factor activityFlowchart of methods. We first identified stage-dependent gene expression alterations, then evaluated the effect of CNV/methylation on expression, and finally built a model to infer stage-dependent activity changes of transcription factors by combining the contributions of CNV/methylation.Back to article page