Fig. 2

ALKBH3 bound promoters have characteristics of ubiquitously expressed gene promoters. ALKBH3 bound promoters have high expression levels (a), often a CpG island (b), higher numbers of bound transcription factors (c), reduced occurrence of the TATA-Box (d), high levels of H3K4me3 (e), and RNA polymerase II (f) as well as highly order nucleosome positioning (g). h Gene ontology shows enrichment of general cellular processes. i The most strongly enriched transcription factor motifs found at ALKBH3 bound promoters. Significance in (a) and (c) has been calculated via an unpaired Student’s t-test. In (b) and (d) the significance has been evaluated using a hypergeometric probability test. The whisker-box plots represent the lower quartile, median and upper quartile of the data with 5 % and 95 % whiskers. TF = Transcription Factor. (*** = P <0.001)