Skip to main content
Fig. 2 | Genome Medicine

Fig. 2

From: Revealing the developmental origin and lineage predilection of neural progenitors within human bone marrow via single-cell analysis: implications for regenerative medicine

Fig. 2

Neural crest-like progenitors are present within adult bone marrow. A1 UMAP visualization of 25 clusters identified in fresh adult human bone marrow, with BMSCs isolated in silico for re-clustering into 5 subpopulations (FC1-FC5) by using specific markers (LEPRhi/PDGFRAhi/ CD45low) which were concentrated at clusters 3 and 16 (A2). B Dot plot showing marker expression levels of each cluster within fresh BMSCs, with FC1 enriched in neural crest marker expression. C Projections of each subpopulation onto the integrated dataset indicated that FC1 was located amongst both neurogenic and osteogenic branches. D Results for biological process analysis, indicating FC1 possessed the potential for neural differentiation

Back to article page

Genome Medicine

ISSN: 1756-994X

Contact us