Table 1 Condensed summary of transcriptional whole blood lupus datasets
From: Analysis of transcriptomic features reveals molecular endotypes of SLE with clinical implications
Dataset | Accession number | Technology | SLE Classification Criteria | Clinical metadata | Clinical trial | No. lupus samples analyzed |
|---|---|---|---|---|---|---|
1 | GSE88884 (ILL-1) | Microarray | ACR | Extensive | NCT01196091 | 813 baseline active female SLE |
2 | GSE88884 (ILL-2) | Microarray | ACR | Extensive | NCT01205438 | 807 baseline active female SLE |
3 | GSE45291 | Microarray | ACR or SLICC | Extensive | None | 266 SLE |
4 | GSE65391 | Microarray | Not specified | Extensive | None | 137 baseline pediatric SLE |
5 | GSE116006 | RNA-seq | ACR | Age, gender, IFN status, drug exposure | NCT01405196 | 160 SLE |
6 | GSE22098 | Microarray | Not specified | Age, gender, ancestry | None | 28 adult SLE |
7 | GSE29536 | Microarray | Not specified | None | None | 27 SLE |
8 | GSE39088 | Microarray | ACR | Age, gender, ancestry | None | 21 SLE |
9 | GSE49454 | Microarray | ACR | Extensive | NCT00920114 | 49 SLE |
10 | GSE61635 | Microarray | Not specified | None | None | 64 SLE |
11 | GSE72509 | RNA-seq | Not specified | Gender, ancestry, Anti-Ro60 status, ISM status | None | 99 SLE |
12 | GSE72747 | Microarray | ACR | Age, gender, SLEDAI, GFR, dsDNA titer | NCT01058343 | 10 baseline SLE |
13 | GSE110174 | Microarray | Not specified | Absolute neutrophils, steroid use | NCT00119678 | 144 SLE |
14 | GSE112087 | RNA-seq | ACR | Age, gender, ancestry | None | 29 female SLE |
15 | GSE138458 | Microarray | ACR | High/low SLEDAI | None | 307 SLE |
16 | GSE185047 | Microarray | ACR | None | NCT02665364 | 177 baseline SLE |
17 | SRX10438277 (PRJNA717024) | RNA-seq | Not specified | Extensive | None | 28 SLE |