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Table 1 Summary of the analytic tools for SRT data analysisa

From: SRT-Server: powering the analysis of spatial transcriptomic data

 

SRT-Server

Giotto

Squidpy

Seurat

SPATA2

10 × Platform

spatialGE

Spaniel

STellaris

Implemented language

R + python

R

python

R

R

 

R

R

R + python

Generic SRT format

Yes

Yes

Yes

Yes

Yes

No

Yes

Yes

Yes

Specific SRT format

Yes

Yes

Yes

Yes

Yes

Yes

No

No

No

Interactive operation

Yes

No

No

No

Yes

Yes

No

No

No

Platform specificity

Yes

No

No

No

No

Yes

No

No

No

Visualization

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Analytic modules

Yes

        

QC

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

SVG

Yes

Yes

Yes

No

Yes

Yes

No

No

No

DECON

Yes

Yes

No

No

Yes

Yes

Yes

No

Yes

Clustering

Yes

Yes

Yes

Yes

Yes

Yes

Yes

Yes

No

CCC

Yes

Yes

Yes

No

No

No

No

No

No

DE

Yes

Yes

No

Yes

Yes

Yes

No

No

No

TRAJ

Yes

No

No

No

Yes

No

No

No

No

ORA

Yes

No

No

No

No

No

No

No

No

Reference

N/A

[13]

[11]

[30]

[14]

N/A

[15]

[16]

[17]

  1. a: All URLs for the existing methods: Giotto: https://rubd.github.io/Giotto_site/; Squidpy: https://squidpy.readthedocs.io/en/latest/; Seurat: https://satijalab.org/seurat/; SPATA2: https://themilolab.github.io/SPATA2/; 10 × Platform: https://support.10xgenomics.com/spatial-gene-expression/software/pipelines/latest/algorithms/overview; spatialGE: https://github.com/FridleyLab/spatialGE; Spaniel: https://github.com/RachelQueen1/Spaniel; STellaris: https://spatial.rhesusbase.com/