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Table 1 Demographic and clinical characteristics of study participants

From: Microbial-derived imidazole propionate links the heart failure-associated microbiome alterations to disease severity

Characteristics

Healthy controls (HC, n = 69)

Heart failure (HF, n = 166)

p-value

Age (years)

51.7 (3.7)

60.2 (9.2)

 < 0.001

Sex, female, n (%)

35 (51%)

44 (27%)

 < 0.001

BMI, m2/kg

25.6 (3.3)

28.3 (5.1)

 < 0.001

Smoke, n (%):

  

 < 0.001

Ex-smoker

0 (0%)

25 (16%)

 

Non-smoker

61 (88%)

82 (53%)

 

Etiology of heart failure, n (%):

   

Ischemic

 

80 (48%)

 

Non-ischemic

 

76 (46%)

 

NYHA class, n (%):

   

II

 

106 (64%)

 

III

 

59 (36%)

 

LVEF, (%)

 

28.7 (7.1)

 

Diabetes, n (%)

 

38 (23%)

 

Hypertension, n (%)

 

46 (38%)

 
  1. Values are expressed as mean ± standard deviation, or percentage. BMI body mass index, NYHA New York Heart Association functional classification, LVEF left ventricular ejection fraction. Statistical significance was tested using Wilcoxon tests (age and BMI) or Fisher’s exact test (sex and smoking status)