Fig. 6

A Overlap of DNA events for three patients which each had three biopsies. The first was diagnosed with spindle cell synovial sarcoma and had 384 and 230 days between relapses. The second was diagnosed with Wilms tumor and had 412 and 88 days between relapses. The third was diagnosed with neuroblastoma and had 168 and 100 days between relapses. “1st” indicates the initial presentation while “2nd” and “3rd” indicate subsequent relapses. The number of overlapping mutations is shown with the percentage of overlapping mutations shown in parenthesis. Genes relevant to cancer are listed. B RNA Z-scores for three subjects each with three biopsies. Biopsy 1 is from the initial presentation, and biopsies 2–3 are from subsequent relapses. Selected genes are shown with the literature-associated drug target in parenthesis. Boxes are highlighted to indicate a molecular target of the drug chosen during the molecular tumor board