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Table 1 Baseline demographic information of the study population

From: Impact of individual level uncertainty of lung cancer polygenic risk score (PRS) on risk stratification

Demographic information

Overall

Case

Control

(N = 30,060)

(n = 17,166)

(n = 12,894)

Gender

   

 Female (n, %)

11,417 (38.0)

6785 (37.4)

4962 (38.5)

 Male (n, %)

18,643 (62.0)

10,711 (62.4)

7932 (61.5)

Age, mean (SD)

62.9 (10.6)

63.7 (10.7)

62.0 (10.6)

Histology

   

 NSCLC (n, %)

13,116 (76.4)

13,116 (76.4)

-

  ADC (n, %)

6539 (38.1)

6539 (38.1)

-

  SCC (n, %)

4180 (24.4)

4180 (24.4)

-

  Others (n, %)

2397 (14.0)

2397 (14.0)

-

 SCLC (n, %)

1763 (10.3)

1763 (10.3)

-

 Others (n, %)

2287 (13.3)

2287 (13.3)

-

Smoking information

   

 Never smoker (n, %)

5805 (19.3)

1702 (9.9)

4103 (31.8)

 Former smoker (n, %)

11,497 (38.2)

6683 (38.9)

4814 (37.3)

 Current smoker (n, %)

12,758 (42.4)

8781 (51.2)

3977 (30.8)

 Pack-years, median (range)

29.4 (0.0, 315.0)

39.0 (0.0, 315.0)

13.0 (0.0, 260.0)

  1. SD standard deviation; NSCLC non-small cell lung cancer; ADC adenocarcinoma, SCC squamous cell carcinoma; SCLC small cell lung cancer