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Table 3 Overlap of commonly identified individuals using different PRS estimators

From: Impact of individual level uncertainty of lung cancer polygenic risk score (PRS) on risk stratification

Thresholds

PRS-16 vs. PRS-16-CV (n,%)

PRS-16 vs. PRS-Bayes (n,%)

PRS-16-CV vs. PRS-Bayes (n,%)

> 60th

10,865 (90)

5998 (50)

6068 (50)

> 70th

7942 (88)

3690 (41)

3726 (41)

> 80th

5161 (85)

1892 (31)

1905 (32)

> 90th

2470 (82)

583 (19)

573 (19)

> 95th

1218 (78)

174 (12)

163 (11)

  1. The number and percentage of individuals that can be commonly identified with the same PRS-based risk groups by any of the two PRS estimators (PRS-16 vs. PRS-16-CV; PRS-16 vs. PRS-Bayes; PRS-16-CV vs. PRS-Bayes) were shown as the threshold of PRS risk increases