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Fig. 2 | Genome Medicine

Fig. 2

From: Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease

Fig. 2

Predictive performance of single features. A Area under the curve (AUC) for individual features, grouped by feature type. Error bars indicate a 95% confidence interval (CI). Asterisks indicate statistical significance after Bonferroni correction for multiple testing. CRF, clinical risk factors; GPSmult, multi-trait multi-ancestry genome-wide polygenic score. Only single features with a lower limit of 95% CI above 50% are shown. B Prevalence of high-risk plaque (HRP) stratified by GPSMult quintiles. Odds ratios are calculated using the first quintile as a reference. Asterisk indicates a statistically significant difference in the estimated odds ratio compared to the reference quintile

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Genome Medicine

ISSN: 1756-994X

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