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Fig. 4 | Genome Medicine

Fig. 4

From: Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease

Fig. 4

Feature importance of the CRF + GPSMult models across cohort groups. A Mean absolute SHAP values, representing the average importance of input features on model prediction, with blue features leading to lower risk and red features leading to higher risk. B Patient-level SHAP values, showing how impactful some features can be in extreme cases. SHAP, Shapley additive explanation; T2D, type 2 diabetes mellitus; GPSMult, multi-trait multi-ancestry genome-wide polygenic score

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Genome Medicine

ISSN: 1756-994X

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