Table 1 Baseline information

Demographics

 Age, years

57 ± 9

60 ± 8

57 ± 9

 Males

699 (48%)

122 (74%)

577 (44%)

Risk factors, n (%)

 Family history

527 (36%)

63 (38%)

464 (36%)

 Current/former smoker

778 (53%)

104 (63%)

674 (52%)

 Dyslipidemia

349 (24%)

42 (25%)

307 (24%)

 Hypertension

517 (35%)

69 (42%)

448 (35%)

 Type 2 diabetes

85 (6%)

16 (10%)

69 (5%)

Type of chest pain, n (%)

 Typical angina

393 (27%)

63 (38%)

330 (25%)

 Atypical angina

497 (34%)

47 (28%)

450 (35%)

 Non-specific chest discomfort

271 (19%)

23 (14%)

248 (19%)

 Dyspnea

301 (21%)

32 (19%)

269 (21%)

Laboratory tests

 Cholesterol medication

349 (24%)

42 (25%)

307 (24%)

Yes

No

Yes

No

Yes

No

 Total cholesterol, mmol/L^a

4.9 ± 1.2

5.5 ± 1.0

5.2 ± 1.6

5.8 ± 1.4

4.9 ± 1.1

5.5 ± 1.0

 LDL cholesterol, mmol/L^a

2.8 ± 1.1

3.4 ± 0.9

3.1 ± 1.2

3.7 ± 0.9

2.8 ± 1.0

3.4 ± 0.9

 HDL cholesterol, mmol/L^a

1.4 ± 0.4

1.5 ± 0.5

1.4 ± 0.4

1.4 ± 0.5

1.5 ± 0.4

1.5 ± 0.4

 Triglyceride, mmol/L^a

1.5 [1.0–2.1]

1.3 [0.9–1.9]

1.6 [1.0–2.3]

1.5 [1.1–2.3]

1.5 [1.0–2.1]

1.3 [0.9–1.9]

Measurements

 Blood pressure medication

517 (35%)

69 (42%)

448 (35%)

Yes

No

Yes

No

Yes

No

 Systolic blood pressure, mm Hg^a

143 ± 19

136 ± 18

144 ± 18

146 ± 19

143 ± 19

135 ± 18

 Diastolic blood pressure, mm Hg^a

84 ± 11

82 ± 11

83 ± 11

86 ± 11

85 ± 11

81 ± 11

 Body mass index^a

26.8 ± 4.2

26.3 ± 3.6

26.8 ± 4.3

 Obstructive CAD at CCTA

341 (23%)

134 (81%)

207 (16%)

 Coronary artery calcium score^a

0 [0–81]

210 [52–624]

0 [0–42]