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Table 2 Plaque subtype prediction

From: Predicting the presence of coronary plaques featuring high-risk characteristics using polygenic risk scores and targeted proteomics in patients with suspected coronary artery disease

Models

Low attenuation (n = 144)

Spotty calcification (n = 181)

Positive remodeling (n = 309)

Napkin ring sign (n = 36)

CRF

71.1 [66.8–75.4]

72.7 [69.0–76.3]

71.9 [68.7–75.0]

76.9 [69.4–84.3]

Protein

67.4 [62.9–71.8]

69.3 [65.3–73.4]

69.0 [65.6–72.3]

74.2 [66.5–81.9]

GPSMult

59.2 [54.3–64.1]

60.2 [55.9–64.5]

62.7 [59.2–66.1]

61.1 [51.6–70.6]

CRF + GPSMult

72.8 [68.6–77.0]

75.1 [71.7–78.5]

74.9 [71.9–77.8]

78.0 [70.0–85.9]

Protein + GPSMult

69.1 [64.9–73.3]

71.5 [67.7–75.3]

71.9 [68.8–75.0]

76.3 [69.3–83.3]

CRF + Protein

71.1 [66.6–75.6]

73.0 [69.3–76.8]

71.5 [68.3–74.7]

79.3 [72.7–85.9]

Full

72.3 [68.3–76.4]

75.0 [71.5–78.6]

74.9 [72.0–77.9]

79.5 [72.8–86.2]

  1. CRF clinical risk factor, GPSMult multi-trait multi-ancestry genome-wide polygenic score
  2. Numbers are the area under the curve with a 95% confidence interval