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Tumor immune microenvironment and immunotherapy

Read the guest editors' editorial and look out for special issue content being published over the next several months.

Genomic medicine multi-disciplinary team approach

Julian Knight and colleagues report on a multi-disciplinary team format for rare disease patients undergoing exome sequencing.

High resolution maps of mutation signature activity

Mark Leiserson and colleagues present their new model SigMa for uncovering mutation signature activity in cancer.

Drug resistance in Mycobacterium tuberculosis

Ashlee Earl and colleagues review the progress and challenges in applying WGS to monitor drug-resistant Mycobacterium tuberculosis.

A Decade of Genome Medicine

2019 is the 10th anniversary of Genome Medicine! This collection revisits some of our favorite articles. 

Reviews, Research Highlights and Commentaries

Read authoritative Reviews, Opinions and other content commissioned by the Genome Medicine Editors from leading researchers:

Reviews

Research Highlights

Commentaries (including Editorials, Comments, Opinions, Q&As and Meeting reports)

Articles

Most accessed articles RSS

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Focus: the Gut Microbiome

Read the latest papers on the gut microbiome across BMC flagship journals.

Oral treatment with Lactobacillus rhamnosus attenuates behavioural deficits and immune changes in chronic social stress
Aadil Bharwani, M. Firoz Mian, Michael G. Surette, John Bienenstock & Paul Forsythe
Published in BMC Medicine 11th January 2017

Bile acid is a significant host factor shaping the gut microbiome of diet-induced obese mice
Xiaojiao Zheng, Fengjie Huang, Aihua Zhao, Sha Lei, Yunjing Zhang, Guoxiang Xie, Tianlu Chen, Chun Qu, Cynthia Rajani, Bing Dong, Defa Li & Wei Jia
Published in BMC Biology 14th December 2017

Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers
Vanessa L. Hale, Patricio Jeraldo, Jun Chen, Michael Mundy, Janet Yao, Sambhawa Priya, Gary Keeney, Kelly Lyke, Jason Ridlon, Bryan A. White, Amy J. French, Stephen N. Thibodeau, Christian Diener, Osbaldo Resendis-Antonio, Jaime Gransee, Tumpa Dutta, Xuan-Mai Petterson, Jaeyun Sung, Ran Blekhman, Lisa Boardman, David Larson, Heidi Nelson & Nicholas Chia
Published in Genome Medicine 31st October 2018

Isolation of novel gut bifidobacteria using a combination of metagenomic and cultivation approaches
Gabriele Andrea Lugli, Christian Milani, Sabrina Duranti, Giulia Alessandri, Francesca Turroni, Leonardo Mancabelli, Danilo Tatoni, Maria Cristina Ossiprandi, Douwe van Sinderen & Marco Ventura
Published in Genome Biology 16th May 2019

Aims and scope

Genome Medicine publishes research and reviews that describe important advances in the application of genetics, genomics and multi-omics to understand, diagnose and treat disease. Areas covered include, but are not limited to: precision medicine, novel methods and software, cancer genomics, disease genomics and epigenomics, immunogenomics, infectious disease, microbiome and systems medicine.

Article collections

Special issue
Tumor immune microenvironment and immunotherapy
Guest editors: Zlatko Trajanoski and Noel de Miranda

Special issue
From genome integrity to cancer
Guest editor: Serena Nik-Zainal

Special issue
Genomics of infection and immunity
Guest editors: Bali Pulendran and Mark Davis

Special issue
Disease Neurogenomics
Guest editors: Joseph Buxbaum and Catalina Betancur

See all article collections

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2018 Journal Metrics

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