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Figure 5 | Genome Medicine

Figure 5

From: Increased hepatic oxidative metabolism distinguishes the action of Peroxisome proliferator-activated receptor δ from Peroxisome proliferator-activated receptor γ in the ob/obmouse

Figure 5

Overview of the key metabolic changes induced by PPARδ stimulation. (a) Metabolic pathways altered in PPARδ agonist treated mice liver. Metabolites increased relative to control tissue are in red; metabolites decreased relative to control tissue are in blue. (b) Linoleate pathway altered in PPARδ agonist treated mice liver. Metabolites increased relative to control tissue are in red; metabolites decreased relative to control tissue are in blue. (c) Linolenate pathway altered in PPARδ agonist treated mice liver. Metabolites increased relative to control tissue are in red; metabolites decreased relative to control tissue are in blue. (d) Metabolic pathways altered in PPARδ agonist treated mice skeletal muscle. Metabolites increased relative to control tissue are in red; metabolites decreased relative to control tissue are in blue.

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Genome Medicine

ISSN: 1756-994X

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