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Figure 4 | Genome Medicine

Figure 4

From: Multi-locus models of genetic risk of disease

Figure 4

Relationship between narrow sense (additive) and broad sense heritability on the risk scale for different disease prevalences ( K ). From simulations of a single population of 106 individuals, with calculated as 4(λ OG - 1)K/(1-K) where λ OG is the recurrence risk of disease in grandchildren of affected grandparents and calculated from Equation 2.

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