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Table 2 Relative risks to relatives of affected individuals calculated within the stochastic simulation for Probit, CRisch and Odds models
| Probit | CRisch | Odds | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| K |
| λ MZ | λ Sib |
| λ MZ | λ Sib |
| λ MZ | λ Sib |
|
| 0.1 | 0.1 | 1.3 | 1.2 | 0.99 | 1.4 | 1.2 | 1.00 | 1.3 | 1.1 | 1.00 |
| 0.1 | 0.5 | 3.2 | 1.9 | 0.87 | 5.6 | 2.6 | 0.84 | 3.9 | 2.1 | 0.85 |
| 0.1 | 0.7 | 4.7 | 2.4 | 0.81 | 7.6 | 3.0 | 0.83 | 6.0 | 2.8 | 0.80 |
| 0.1 | 0.95 | 7.8 | 3.1 | 0.82 | 9.7 | 3.2 | 0.92 | 9.3 | 3.2 | 0.90 |
| 0.01 | 0.1 | 1.9 | 1.4 | 0.97 | 2.4 | 1.5 | 1.00 | 1.7 | 1.3 | 1.03 |
| 0.01 | 0.5 | 13.0 | 4.4 | 0.68 | 51.7 | 9.9 | 0.53 | 34.8 | 8.1 | 0.54 |
| 0.01 | 0.7 | 26.6 | 7.0 | 0.54 | 76.8 | 12.3 | 0.51 | 62.3 | 11.3 | 0.49 |
| 0.01 | 0.95 | 67.3 | 11.7 | 0.49 | 97.0 | 13.0 | 0.57 | 94.6 | 12.9 | 0.57 |
| 0.001 | 0.1 | 2.8 | 1.7 | 0.96 | 4.0 | 2.0 | 1.00 | 1.2 | 1.1 | 1.06 |
| 0.001 | 0.5 | 54.8 | 10.5 | 0.49 | 516.5 | 41.6 | 0.30 | 342.5 | 34.0 | 0.30 |
| 0.001 | 0.7 | 157.8 | 20.6 | 0.37 | 796.8 | 51.4 | 0.30 | 638.5 | 49.5 | 0.26 |
| 0.001 | 0.95 | 599.8 | 47.5 | 0.27 | 989.9 | 57.6 | 0.30 | 968.6 | 55.9 | 0.31 |
is an input parameter for the Probit model. For each τ is estimated from the Probit model simulation and used as input to the CRisch and Odds model simulations. is used as the benchmark as τ is dependent on n, p and K.
