Figure 1From: High-throughput sequencing identifies STAT3 as the DNA-associated factor for p53-NF-κB-complex-dependent gene expression in human heart failureGenomic structure of mir-21. Location of a previously described promoter (miPPR-21) [30], our putative regulatory region (GIS) [19], a H3K4me3 binding site as determined by previous ChIP-seq [32], and a STAT3 binding site according to Loffler et al. [34]. Both miPPR-21 and GIS regions are highly conserved.Back to article page