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Table 1 Proteins having some evidence (P < 0.05) of difference in concentration between coronary heart disease cases and controls

From: Novel proteins associated with risk for coronary heart disease or stroke among postmenopausal women identified by in-depth plasma proteome profiling

Protein Description Log(base2) case vs control ratio P-valuea FDRa
B2M Beta-2-microglobulin. 0.212 5.07e-05 0.0176
ORM1 Alpha-1-acid glycoprotein 1 0.120 0.000182 0.0315
IGFALS Insulin-like growth factor-binding protein complex acid labile chain -0.112 0.000384 0.0443
THBS1 Thrombospondin-1 -0.632 0.00133 0.0749
LPA Apolipoprotein(A) 0.347 0.00138 0.0749
CFD Complement factor D preproprotein 0.210 0.00141 0.0749
PRG4 Isoform C of proteoglycan 4 0.232 0.00152 0.0749
GPX3 Glutathione peroxidase 3 -0.224 0.00308 0.133
IGFBP1 Insulin-like growth factor-binding protein 1 0.423 0.00381 0.146
MST1 Hepatocyte growth factor-like protein homolog -0.306 0.00592 0.205
ITIH2 Inter-alpha-trypsin inhibitor heavy chain H2 -0.140 0.00786 0.247
ENO1 Isoform alpha-enolase of alpha-enolase -0.418 0.00950 0.255
C9 Complement component C9 0.0827 0.00989 0.255
SFTPB Pulmonary surfactant-associated protein B precursor 0.551 0.0112 0.255
FHL1 cDNA FLJ55259 highly similar to four and a half lim domains protein 1 -0.481 0.0116 0.255
CRISP3 cDNA FLJ75207 0.147 0.0118 0.255
SERPIND1 Serpin peptidase inhibitor clade D (heparin cofactor) member 1 0.210 0.0176 0.334
CD5L CD5 antigen-like 0.152 0.0181 0.334
SOD3 Extracellular superoxide dismutase [Cu-Zn] 0.453 0.0183 0.334
TPI1 Triosephosphate isomerase 1 isoform 2 -0.144 0.0232 0.401
C1QB Complement component 1 Q subcomponent B chain precursor -0.106 0.0271 0.407
ATRN Isoform 1 of attractin -0.151 0.0274 0.407
INHBE Inhibin beta E chain 0.384 0.0284 0.407
CHRDL2 Isoform 2 of chordin-like protein 2 -0.647 0.0287 0.407
LIMS1 cDNA FLJ55516 highly similar to particularly interesting new Cys-His protein -0.412 0.0318 0.407
VASP Vasodilator-stimulated phosphoprotein -0.499 0.0356 0.407
C8A Complement component C8 alpha chain 0.170 0.0359 0.407
C2 Complement C2 (fragment) -0.230 0.0361 0.407
CD14 Monocyte differentiation antigen CD14 0.105 0.0361 0.407
GC Vitamin D-binding protein -0.0451 0.0364 0.407
MTPN Myotrophin -0.240 0.0372 0.407
SERPINF2 Serpin peptidase inhibitor, clade F, member 2 -0.110 0.0383 0.407
ACTA2 Actin aortic smooth muscle -1.22 0.0388 0.407
TAGLN2 Transgelin-2 -0.186 0.0426 0.433
FERMT3 Isoform 2 of fermitin family homolog 3 -0.560 0.0462 0.454
F12 Coagulation factor XII -0.147 0.0472 0.454
AFM Afamin -0.0764 0.0490 0.458
  1. aP-value = significance level for no difference in protein concentration; FDR = estimated false discovery rate.