From genotype to EEG endophenotype: a route for post-genomic understanding of complex psychiatric disease?

Table 1 Heritability estimates for EEG/ERP traits*

EEG/ERP trait	Heritability estimates	References
Power α band	86-96%	[30–32]
Power θ band	80-90%	[30, 32]
Power β band	70-82%	[30, 32]
Peak frequency α band	71-83%	[33, 34]
Path length α band	48-68%	[31]
Cluster coefficient β band	25-40%	[31]
Path length β band	29-42%	[31]
Cluster coefficient α band	37-45%	[31]
Long range temporal correlations α band	47%	[35]
Long range temporal correlations β band	42%	[35]
Frontal EEG asymmetry α band	1-37%	[36]
P50 amplitude attenuation	34%	[47]
N1 amplitude attenuation	45%	[47]
P2 amplitude attenuation	54%	[47]
Mismatch negativity	58%	[37]
Posterior N1 amplitude	50%	[38]
Posterior N1 latency	45%	[38]
Anterior N1 amplitude	22%	[38]
Anterior N1 latency	43%	[38]
Go/Nogo difference N2 amplitude	53%	[39]
Error positivity	52%	[40]
Error-related negativity	47%	[40]
P3 amplitude	50-80%	[37, 41, 42]
P3 latency	38-50%	[37, 41, 42]
Onset lateralized readiness potential	54-62%	[43]
Peak lateralized readiness potential latency	38-45%	[43]

*Data are from studies comparing the resemblance in monozygotic twins with that in dizygotic twins. If a measure was available at multiple electrodes, the electrodes with highest amplitude were selected. A range of heritabilities reflects either the variation in estimates across multiple studies or across multiple age groups within a single study.

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