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Figure 2 | Genome Medicine

Figure 2

From: Overcoming bias and systematic errors in next generation sequencing data

Figure 2

Effect of mappability and GC content on coverage. (a) Mean tag counts in 50-bp bins, with error bars, from a naked DNA sample from a ChIP-Seq experiment, showing that they depend on mappability and GC content. (b) 97.4% of bins have GC percentages between 0.2% and 0.56%, as marked by the vertical dashed lines. This figure is reproduced with permission from Kuan et al. [21].

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