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Table 3 Top significant markers (-Log 10(p) > 6)) after adjusting for DRB1*15:0 1 among the 700-independent-gene set

From: Modeling the cumulative genetic risk for multiple sclerosis from genome-wide association data

rs ID Position Chrom. Gene name Allele 1 Allele 2 -Log10 p OR Lower CL Upper CL
rs9268148 32367505 6 C6orf10 A G 13.13 0.58 0.50 0.67
rs1611715 29937461 6 HLA-G C A 11.49 0.74 0.68 0.81
rs7772297 31436805 6 HLA-B C G 9.14 1.40 1.26 1.56
rs4939490 60550227 11 CD6 G C 9.00 1.30 1.19 1.42
rs9275596 32789609 6 HLA-DQA2 T C 7.85 0.76 0.69 0.84
rs10244467 22584456 7 IL6 T C 7.23 0.57 0.47 0.70
rs9596270 49740441 13 DLEU1 T C 7.08 1.56 1.31 1.85
rs12025416 116750329 1 CD58 C T 6.83 0.69 0.59 0.80
rs6836440 100405684 4 ADH4 A G 6.74 0.68 0.58 0.79
rs7137953 119357405 12 GATC C T 6.47 0.77 0.70 0.85
rs10846336 16413619 12 MGST1 T C 6.43 0.42 0.30 0.59
rs931555 35839334 5 IL7R C T 6.41 1.25 1.15 1.36
rs10203141 179015804 2 OSBPL6 C G 6.40 0.81 0.75 0.88
rs2328523 20575342 6 E2F3 G A 6.28 0.79 0.72 0.87
rs4368946 98497864 8 TSPYL5 T C 6.25 0.70 0.61 0.80
rs3934035 281714 3 CHL1 C T 6.23 0.46 0.34 0.62
rs17062281 73654880 13 KLF12 C G 6.13 0.44 0.31 0.61
rs1356122 155666264 3 GPR149 G C 6.13 1.26 1.14 1.40
rs4447 31599694 22 SYN3 T C 6.10 0.74 0.66 0.83
rs655763 108682027 11 C11orf87 C T 6.03 1.59 1.32 1.92
rs12419184 125561518 11 RPUSD4 C T 6.03 0.72 0.63 0.82
  1. Chrom., chromosome; lower CL, lower bound of the confidence interval; OR, odds ratio; upper CL, upper bound of the confidence interval.