Association between the sTIN subtype and patient survival in the CRC test series. (a) Differences between the amounts of deviating exon inclusion and skipping per sample were used to identify patients with sTIN tumors (threshold at ± 0.7 on the log-ratio scale). (b) Disease-specific survival among patients in the test series stratified by the sTIN subtype. In this analysis, deaths from CRC were considered events (n = 41). Patients who survived throughout the 10 years of follow-up were censored (n = 42). Recurrences (n = 2 among patients who survived) were ignored.