Table 2 FDA-approved biomarkers
From: Biomarkers in solid organ transplantation: establishing personalized transplantation medicine
Organ | Sample | Proposed mechanism | Biomarker | References |
|---|---|---|---|---|
Heart | Blood (PBMCs, mRNA) | Gene-expression-based diagnostic score distinguishes stable from acute heart allograft rejection patients and mild from severe AR | AlloMap (11-gene panel) | |
Heart, liver, lung, kidney | Serum (protein) | T-cell activation status indicates risk of AR, under-/over-immunosuppression | ImmuKnow (T-cell-stimulation-dependent iATP levels) |