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Table 2 Table of haplotypes with odds ratios

From: Identification of improved IL28B SNPs and haplotypes for prediction of drug response in treatment of hepatitis C using massively parallel sequencing in a cross-sectional European cohort

NUMBER HAPLOTYPE HAPLOTYPE TAGGING SNPA FREQUENCY (%) RESPONDERS (%) NON-RESPONDERS (%) P-VALUE ORB (95% CI)
1 ATTGATCCTCTG rs8109886 43.2 48.4 39.6 4.00 × 10-4 0.70 (0.57-0.85)
2 GCCAGCTGTAGA rs8099917/rs7248668 23.8 16.5 30.4 9.51 × 10-11 2.20 (1.72-2.80)
3 GCTAGCTCCATG rs10853727 10.3 10.1 10.6 0.77 1.04 (0.75-1.43)
4 ATTGATCCTATG   9.8 12.3 7.8 2.40 × 10-3 0.60 (0.43-0.83)
5 ATTAACTCTATG   1.9 2.2 1.7 0.47 0.79 (0.39-1.60)
6 GCCAGCTGTATG   1.4 1.1 1.6 0.39 1.49 (0.62-3.56)
  1. The distribution of the six haplotypes in haplotype block 2 (Fig 4) bound by SNPs rs12980275 and rs7248668. The order is: rs12980275, rs12982533, rs8105790, rs688187, rs11881222, rs8103142, rs12979860, rs48031221, rs10853727, rs8109886, rs8099917, rs7248668. aSNP in the haplotype block 2 that tag the respective haplotypes. bORs have been calculated as carriage of the haplotype vs non-carriage of the haplotype.