Figure 2

Similarities for 83 metastatic test samples. (a) A comparison of the test samples' similarities to the healthy tissue where the metastasis was found (y-axis) and the cancer of origin for the metastasis (x-axis). The spheres are colored according the site of the metastasis ('target tissue'). The gray diagonal line indicates a boundary, above which the similarity to the target tissue is greater than the similarity to the sample's original cancer. Only ten samples display this behavior, and all but one of these are lymph node metastases. (b) A comparison of the test samples' similarities to a representative cancer of the tissue where the metastasis was found (y-axis) and the cancer of origin for the metastasis (x-axis). The triangles are colored according to the site of the metastasis ('target tissue'). The gray diagonal line indicates a boundary above which the similarity to the cancer of the target tissue is greater than the similarity to the sample's original cancer. As can be seen, most samples fall below this line.