Figure 1
From: Identification of cis-regulatory sequence variations in individual genome sequences
Classification of the regulatory sequences in a gene that can be modified by genetic variation. The four colored groups reflect mutations that have a deleterious impact on gene transcription (class 1 in red), splicing (class 2 in blue), RNA stability (class 3 in orange) and translation (class 4 in green). A fifth class, non-coding RNA interaction sites, is not shown as sites can occur throughout DNA and RNA sequences.