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Table 1 Demographic and metabolic characteristics of the study population, shown for patients, their unaffected co-twins, patients and their co-twins combined (discordant twin pairs), and the controls

From: Phospholipids and insulin resistance in psychosis: a lipidomics study of twin pairs discordant for schizophrenia

Characteristic

Controls

Unaffected co-twins

Patients

P(F-test)

N

34

19

19

 

Monozygotic

20 (10 pairs)

7

7

 

Female

24

13

13

 

Age (years)a

53.4 (50.2, 56.6)

51.0 (46.4, 55.6)

51.0 (46.4, 55.6)

 

Diabetes

0

1

7

 

Antipsychotic medication (atypical antipsychotics)b

0

0

15 (14)

 

Cholesterol medication

2

0

6

 

BMI

25.4 (23.8, 27.0)**

25.7 (24.0, 27.5)**

29.2 (26.5, 31.9)

0.020

Insulinc

7.7 (5.9, 9.9)

8.9 (6.9, 11.6)*

14.1 (9.1, 21.7)

0.085

Glucosec

5.07 (4.78, 5.38)

5.30 (4.54, 6.19)

5.76 (4.87, 6.80)

0.40

HOMA-IRc

1.72 (1.30, 2.29)

2.11 (1.52, 2.93)**

3.61 (2.22, 5.86)

0.062

  1. aData for this and other variables are shown as mean (95% confidence interval). bAccording to self-report. cGeometric means and confidence intervals; statistics estimated from log10-transformed data. *P < 0.1, **P < 0.05 (post-hoc analysis using Tukey all-pair comparisons versus the patient group; no comparisons were significant between the controls and unaffected co-twins). BMI, body mass index; HOMA-IR, Homeostasis Model Assessment index.