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Table 2 Description of lipid clusters obtained from lipidomics platform

From: Phospholipids and insulin resistance in psychosis: a lipidomics study of twin pairs discordant for schizophrenia

Cluster name

Cluster size

Description

Representative abundant lipids

P(F-test)

LC1

68

Mainly ether lipids

PE(36:6e), PC(34:4e)

0.39

LC2

211

Sphingomyelins, major phospholipids

SM(d18:1/18:0), SM(d18:1/24:1), PC(34:2)

0.69

LC3

49

PUFA-containing PCs and PEs

PC(38:6), PE(38:5)

0.91

LC4

25

LysoPCs

lysoPC(18:0), lysoPC(20:3)

0.096a

LC5

76

Abundant TGs

TG(16:0/18:1/18:1), TG(18:1/18:2/18:1)

0.061b

LC6

35

Long-chain TGs; PUFA-containing TGs

TG(56:6), TG(58:8), TG(58:9)

0.25

LC7

66

Mainly shorter-chain SFAs and MUFA-containing TGs

TG(14:0/16:0/18:1), TG(14:0/16:0/18:0)

0.65

  1. aTukey's all-pair comparison: P = 0.12 (patients versus co-twins), P = 0.078 (co-twins versus controls), P = 0.56 (patients versus controls). bTukey's all-pair comparison: P = 0.039 (patients versus co-twins), P = 0.44 (co-twins versus controls), P = 0.24 (patients versus controls). LC, LC, lipid cluster; lysoPC, lysophosphatidylcholine; MUFA, monounsaturated fatty acid; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PUFA, polyunsaturated fatty acid; SFA, saturated fatty acid; SM, sphingomyelin; TG, triglyceride.