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Table 2 Description of lipid clusters obtained from lipidomics platform

From: Phospholipids and insulin resistance in psychosis: a lipidomics study of twin pairs discordant for schizophrenia

Cluster name Cluster size Description Representative abundant lipids P(F-test)
LC1 68 Mainly ether lipids PE(36:6e), PC(34:4e) 0.39
LC2 211 Sphingomyelins, major phospholipids SM(d18:1/18:0), SM(d18:1/24:1), PC(34:2) 0.69
LC3 49 PUFA-containing PCs and PEs PC(38:6), PE(38:5) 0.91
LC4 25 LysoPCs lysoPC(18:0), lysoPC(20:3) 0.096a
LC5 76 Abundant TGs TG(16:0/18:1/18:1), TG(18:1/18:2/18:1) 0.061b
LC6 35 Long-chain TGs; PUFA-containing TGs TG(56:6), TG(58:8), TG(58:9) 0.25
LC7 66 Mainly shorter-chain SFAs and MUFA-containing TGs TG(14:0/16:0/18:1), TG(14:0/16:0/18:0) 0.65
  1. aTukey's all-pair comparison: P = 0.12 (patients versus co-twins), P = 0.078 (co-twins versus controls), P = 0.56 (patients versus controls). bTukey's all-pair comparison: P = 0.039 (patients versus co-twins), P = 0.44 (co-twins versus controls), P = 0.24 (patients versus controls). LC, LC, lipid cluster; lysoPC, lysophosphatidylcholine; MUFA, monounsaturated fatty acid; PC, phosphatidylcholine; PE, phosphatidylethanolamine; PUFA, polyunsaturated fatty acid; SFA, saturated fatty acid; SM, sphingomyelin; TG, triglyceride.