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Table 3 Number of metabolites in the major biochemical classes detected in various human tissues

From: Cancer detection and biopsy classification using concurrent histopathological and metabolomic analysis of core biopsies

  Tissue type
Biochemical super pathway Adrenal gland (1) Colon (4) Lung (1) Muscle (4) Pancreas (3) Small intestine (4) Spleen (1) Stomach (4) Prostate (8) Kidney (3)
Amino acid 69 80 71 77 71 74 62 80 70 81
Peptide 35 40 36 37 42 43 38 42 6 24
Carbohydrate 25 26 27 28 26 25 23 27 21 19
Energy 8 8 8 8 8 8 8 8 10 7
Lipid 102 129 112 122 117 124 90 125 101 107
Nucleotide 23 28 24 25 26 26 24 27 20 22
Cofactors and vitamins 8 12 9 10 8 9 7 10 13 13
Xenobiotics 13 17 12 15 13 15 10 15 17 20
Total 283 340 299 322 311 324 262 334 260 293
  1. Adrenal gland, colon, lung, muscle, pancreas, small intestine, spleen, and stomach samples were collected from beating heart donors just prior to the withdrawal of support, placed immediately in 80% methanol and incubated for 24 to 72 h at room temperature. Prostate refers to benign human tissue biopsy samples collected post-prostatectomy from regions of the prostate that did not contain cancer and processed in 80% methanol as described. Kidney refers to the fresh frozen normal human kidney tissue analyzed in the incubation time course experiment reported in Table 1. The number of metabolites detected in each biochemical class is indicated. The number of samples analyzed for each tissue type is indicated in parentheses.