Metabolomic analysis of rat serum in streptozotocin-induced diabetes and after treatment with oral triethylenetetramine (TETA)

Table 3 Metabolite shown as statistically significant (P < 0.05) when comparing streptozotocin-induced diabetic/untreated and streptozotocin-induced diabetic/triethylenetetramine-treated rats in both independent studies

	Discovery		Validation
Metabolite	P-value	Ratio (diabetic treated/non-diabetic treated)	P-value	Ratio (diabetic treated/non-diabetic treated)
Hydroxybutanoic acid AND/OR methyl-hydroxybutanoic acid	0.00898	1.25	0.00898	1.78

For multiple metabolite identifications for a single metabolic feature, each unique metabolite is separated by AND/OR.

ISSN: 1756-994X