Figure 5
From: Consensus: a framework for evaluation of uncertain gene variants in laboratory test reporting
Protein view with Consensus scoring. (a, b) Proposed visualization of Consensus scoring using known gene variants plotted on the RET_HUMAN (UniProt #P07949) protein (image courtesy of the Human Protein Reference Database [56]) and weighted algorithm output with radar plots to summarize predictor evidence for pathogenic gene variant C634R (a), scoring 359, and benign variant G691S (b) with a Consensus score of 108.