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Table 3 Stroke odds ratio for E-alone and E+P, by genotype of SNPs in F13A1 region

From: Exploring the interaction between SNP genotype and postmenopausal hormone therapy effects on stroke risk

   SNP genotype   
  Number of cases GG GA AA   
   OR 95% CI OR 95% CI OR 95% CI p-2df p-1df
rs2154299          
   E-alone          
All 351 1.372 (1.086, 1.732) 0.920 (0.547, 1.548) 0.511 (0.094, 2.791) 0.21471 0.08111
Ischemic 263 1.614 (1.226, 2.124) 1.022 (0.566, 1.846) 0.682 (0.114, 4.079) 0.27045 0.10598
Hemorrhagic 48 0.756 (0.404, 1.414) 0.341 (0.069, 1.689) NA (NA, NA) 0.34339 0.34339
   E+P          
All 438 1.517 (1.218, 1.889) 0.685 (0.459, 1.023) 0.238 (0.027, 2.13) 0.00066 0.00013
Ischemic 319 1.553 (1.198, 2.013) 0.68 (0.426, 1.087) 0.238 (0.027, 2.13) 0.00229 5.00E-04
Hemorrhagic 76 1.199 (0.724, 1.988) 0.635 (0.226, 1.784) NA (NA, NA) 0.27362 0.27362
rs12194855          
   E-alone          
All 351 0.682 (0.114, 4.079) 0.890 (0.532, 1.492) 1.372 (1.086, 1.732) 0.25707 0.10080
Ischemic 263 0.682 (0.114, 4.079) 1.022 (0.566, 1.846) 1.614 (1.226, 2.124) 0.27045 0.10598
Hemorrhagic 48 NA (NA, NA) 0.341 (0.069, 1.689) 0.756 (0.404, 1.414) 0.34339 0.34339
   E+P          
All 438 0.238 (0.027, 2.130) 0.702 (0.471, 1.046) 1.509 (1.212, 1.88) 0.00097 2.00E-04
Ischemic 319 0.238 (0.027, 2.130) 0.703 (0.442, 1.118) 1.543 (1.190, 2.000) 0.00337 0.00076
Hemorrhagic 76 NA (NA, NA) 0.635 (0.226, 1.784) 1.199 (0.724, 1.988) 0.27362 0.27362
  1. OR, estimated intervention odds ratio. p-2df, P-value regressing randomization assignment on indicator for one or two minor alleles. p-1df, P-value regressing randomization assignment on number of minor alleles. NA indicates information (data) not available. CI, confidence interval.