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Table 3 Resources with information connecting proteins and drugs

From: Getting personalized cancer genome analysis into the clinic: the challenges in bioinformatics

Name Details URL
ChEBI (Chemical Entities of Biological Interest) Contains more than half a million chemical compounds classified according to their biological activity http://www.ebi.ac.uk/chebi/
DrugBank Contains detailed chemical, pharmacological and pharmaceutical data linked with information on the sequence, structure and pathways of potential targets. The database contains information on almost 500 drugs http://www.drugbank.ca
Resources from Peer Bork's group, including STITCH, SuperDrug, SuperNatural and SuperTarget/Matador Bork's group has developed a number of systems that help link drugs to their protein and genomic targets, including data on adverse drug effects and symptoms http://www.embl.de/~bork
PharmGKB Repository linking genomic information on 2,500 genetic variants with clinical data derived from pharmacogenomics studies, and the corresponding diseases and phenotypes http://www.pharmgkb.org
TTD (Therapeutic Target Database) Contains data for relations between 2,000 targets and more than 15,000 drugs, including information extracted from clinical trials http://xin.cz3.nus.edu.sg/group/ttd/ttd.asp