Figure 1
From: Mass spectrometry for translational proteomics: progress and clinical implications
Simultaneous MS analyses for understanding complex systems. Simultaneous study of the genome, transcriptome, proteome, glycome, lipidome and metabolome by MS provides a systems approach to understanding different conditions and disease states through analysis of variations in DNA, RNA, peptides/proteins, lipids and metabolites, respectively, in an organ, tissue, blood or other sample, or organism. MS is one of the only analytical tools that can perform measurements at each -omic level, and thus can provide a better understanding of molecular mechanisms and how they affect each other. PTM, post-translational modification.