TY - JOUR AU - Takahashi, K. AU - Yamanaka, S. PY - 2006 DA - 2006// TI - Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors JO - Cell VL - 126 UR - https://doi.org/10.1016/j.cell.2006.07.024 DO - 10.1016/j.cell.2006.07.024 ID - Takahashi2006 ER - TY - JOUR PY - 2012 DA - 2012// TI - Induced pluripotent stem cells from patients with Huntington's disease show CAG-repeat-expansion-associated phenotypes JO - Cell Stem Cell VL - 11 UR - https://doi.org/10.1016/j.stem.2012.06.001 DO - 10.1016/j.stem.2012.06.001 ID - ref2 ER - TY - JOUR AU - An, M. C. AU - Zhang, N. AU - Scott, G. AU - Montoro, D. AU - Wittkop, T. AU - Mooney, S. AU - Melov, S. AU - Ellerby, L. M. PY - 2012 DA - 2012// TI - Genetic correction of Huntington's disease phenotypes in induced pluripotent stem cells JO - Cell Stem Cell VL - 11 UR - https://doi.org/10.1016/j.stem.2012.04.026 DO - 10.1016/j.stem.2012.04.026 ID - An2012 ER - TY - JOUR AU - Zhang, N. AU - An, M. C. AU - Montoro, D. AU - and Ellerby, L. M. PY - 2010 DA - 2010// TI - Characterization of human Huntington's disease cell model from induced pluripotent stem cells JO - PLoS Currents VL - 2 UR - https://doi.org/10.1371/currents.RRN1193 DO - 10.1371/currents.RRN1193 ID - Zhang2010 ER - TY - JOUR AU - Camnasio, S. AU - Carri, A. D. AU - Lombardo, A. AU - Grad, I. AU - Mariotti, C. AU - Castucci, A. AU - Rozell, B. AU - Riso, P. L. AU - Castiglioni, V. AU - Zuccato, C. AU - Rochon, C. AU - Takashima, Y. AU - Diaferia, G. AU - Biunno, I. AU - Gellera, C. AU - Jaconi, M. AU - Smith, A. AU - Hovatta, O. AU - Naldini, L. AU - Di Donato, S. AU - Feki, A. AU - Cattaneo, E. PY - 2012 DA - 2012// TI - The first reported generation of several induced pluripotent stem cell lines from homozygous and heterozygous Huntington's disease patients demonstrates mutation related enhanced lysosomal activity JO - Neurobiol Dis VL - 46 UR - https://doi.org/10.1016/j.nbd.2011.12.042 DO - 10.1016/j.nbd.2011.12.042 ID - Camnasio2012 ER - TY - JOUR AU - Mochel, F. AU - Haller, H. G. PY - 2011 DA - 2011// TI - Energy deficit in Huntington disease: why it matters JO - J Clin Invest VL - 121 UR - https://doi.org/10.1172/JCI45691 DO - 10.1172/JCI45691 ID - Mochel2011 ER - TY - JOUR AU - Zuccato, C. AU - Cattaneo, M. PY - 2009 DA - 2009// TI - Brain-derived neurotrophic factor in neurodegenerative diseases JO - Nat Rev Neurol VL - 5 UR - https://doi.org/10.1038/nrneurol.2009.54 DO - 10.1038/nrneurol.2009.54 ID - Zuccato2009 ER - TY - JOUR AU - Xie, Y. AU - Hayden, M. R. AU - Xu, B. PY - 2010 DA - 2010// TI - BDNF overexpression in the forebrain rescues Huntington's disease phenotypes in YAC128 mice JO - J Neurosci VL - 30 UR - https://doi.org/10.1523/JNEUROSCI.1637-10.2010 DO - 10.1523/JNEUROSCI.1637-10.2010 ID - Xie2010 ER - TY - CHAP AU - La Spada, A. R. AU - Weydt, P. AU - Vineda, V. V. ED - Lo, D. C. ED - Hughes, R. E. PY - 2011 DA - 2011// TI - Huntington's disease pathogenesis: mechanisms and pathways BT - Neurobiology of Huntington's Disease: Applications to Drug Discovery PB - CRC Press CY - Boca Raton, FL ID - La Spada2011 ER - TY - JOUR AU - Tsunemi, T. AU - Ashe, T. D. AU - Morrison, B. E. AU - Soriano, K. R. AU - Au, J. AU - Vazquez Roque, R. A. AU - Lazarowski, E. R. AU - Damian, V. A. AU - Masliah, E. AU - La Spada, A. R. PY - 2012 DA - 2012// TI - PGC-1α rescues Huntington's disease proteotoxicity by preventing oxidative stress and promoting TFEB function JO - Sci Transl Med VL - 4 ID - Tsunemi2012 ER -