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Table 9 Summary of diabetes loci ranked by MeSHOP similarity

From: Inferring novel gene-disease associations using Medical Subject Heading Over-representation Profiles

Locus

Entrez Gene ID

Predicted similarity score

Rank

Percentile

Direct association

IDE

3416

7.59E+07

186

0.01

7.93E-02

TCF7L2

6934

5.91E+07

421

0.02

3.30E-03

EXT2

2132

2.96E+07

2616

0.10

NA

HHEX

3087

2.18E+07

4631

0.18

NA

KIF11

3832

1.87E+07

5985

0.24

NA

ALX4

60529

1.55E+07

8313

0.33

NA

SLC30A8

169026

1.55E+07

8352

0.33

NA

LOC387761

387761

NA

NA

NA

NA

  1. Loci identified by (Sladek et al. [42]) were ranked by MeSHOP similarity (L2 of log-p of overlapping terms only). Direct association scores are the Bonferroni corrected P-values generated using the February 2007 datasets. NA