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Table 9 Summary of diabetes loci ranked by MeSHOP similarity

From: Inferring novel gene-disease associations using Medical Subject Heading Over-representation Profiles

Locus Entrez Gene ID Predicted similarity score Rank Percentile Direct association
IDE 3416 7.59E+07 186 0.01 7.93E-02
TCF7L2 6934 5.91E+07 421 0.02 3.30E-03
EXT2 2132 2.96E+07 2616 0.10 NA
HHEX 3087 2.18E+07 4631 0.18 NA
KIF11 3832 1.87E+07 5985 0.24 NA
ALX4 60529 1.55E+07 8313 0.33 NA
SLC30A8 169026 1.55E+07 8352 0.33 NA
LOC387761 387761 NA NA NA NA
  1. Loci identified by (Sladek et al. [42]) were ranked by MeSHOP similarity (L2 of log-p of overlapping terms only). Direct association scores are the Bonferroni corrected P-values generated using the February 2007 datasets. NA