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Table 5 Survival tests for 29 genes distinguishing GNS from NS lines

From: Digital transcriptome profiling of normal and glioblastoma-derived neural stem cells identifies genes associated with patient survival

  

TCGA data set

Gravendeel data set (glioblastoma cases)

Gene

Category

Coefficienta

P

Probesetb

Coefficienta

P

ADD2

Upregulated

-0.13

0.2858

237336_at

-0.17

0.1420

CD9

Upregulated

0.18

0.0731

201005_at

0.17

0.0689

CEBPB

Upregulated

0.19

0.1028

212501_at

0.17

0.0651

DDIT3

Upregulated

0.17

0.0128

209383_at

0.09

0.2777

FOXG1

Upregulated

0.13

0.0861

206018_at

0.11

0.0380

HMGA2

Downregulated

0.13

0.1456

1561633_at

-0.84

0.2459

HOXD10

Upregulated

0.12

0.0108

229400_at

0.15

0.0021

IRX2

Downregulated

-0.19

0.2346

228462_at

-0.20

4.4 × 10-4

LMO4

Upregulated

0.24

0.1046

209205_s_at

0.20

0.1435

LYST

Upregulated

0.05

0.5590

203518_at

0.10

0.4151

MAF

Downregulated

0.10

0.5873

209348_s_at

0.38

0.0074

MAP6

Downregulated

0.16

0.3063

235672_at

-0.30

0.0087

MT2A

Upregulated

0.16

0.1554

212185_x_at

0.27

0.0127

MYL9

Downregulated

0.08

0.3764

201058_s_at

0.15

0.0252

NDN

Downregulated

-0.04

0.4874

209550_at

-0.22

6.0 × 10-5

NELL2

Downregulated

0.08

0.1021

203413_at

0.14

0.0215

PDE1C

Upregulated

0.20

0.0105

236344_at

0.21

0.0134

PLA2G4A

Upregulated

-0.06

0.3198

210145_at

0.30

2.9 × 10-4

PLCH1

Downregulated

0.10

0.3165

214745_at

0.45

0.0094

PLS3

Upregulated

0.13

0.0381

201215_at

0.30

0.0069

PRSS12

Upregulated

-0.11

0.1865

213802_at

0.20

0.0296

PTEN

Downregulated

-0.53

0.0047

228006_at

-0.40

0.0062

SDC2

Downregulated

0.22

0.0044

212158_at

0.28

5.8 × 10-4

ST6GALNAC5

Downregulated

0.01

0.9116

220979_s_at

0.08

0.2416

SULF2

Upregulated

-0.11

0.1525

233555_s_at

-0.15

0.0930

SYNM

Downregulated

-0.06

0.5620

212730_at

0.08

0.2613

TAGLN

Downregulated

0.03

0.5947

205547_s_at

0.17

0.0030

TES

Downregulated

-0.05

0.5759

202720_at

0.07

0.5499

TUSC3

Downregulated

-0.14

0.0079

209227_at

-0.18

0.0060

  1. aFitted coefficient from Cox model; a positive coefficient indicates that higher expression is associated with poor survival and a negative coefficient indicates the opposite. bFor the Gravendeel data set, the result for the most significant probeset interrogating the gene is shown.