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Table 2 Common SNPs across the IL28B gene region have very different minor allele frequencies in the major ethnic groups

From: Pharmacogenomics of hepatitis C infections: personalizing therapy

Location SNP OR %CEU %CHI %YRI
5' rs7248668 2.24b 17 7 6
5' rs8099917c 1.91b 17 8 6
5' rs8109886 0.67a 43 7 80
5', CpG rs4803221 2.24b 17 7 18
5', CpG rs12979860c 1.99b 32 8 60
Exon 2 rs8103142 1.50b 27 4 56
Intron 2 rs11881222 2.02b 30 7 31
3' rs688187 1.94b 32 7 59
3' rs8105790 1.63b 17 7 19
3' rs12982533 2.01b 31 8 39
3' rs12980275 1.79b 31 8 51
  1. aMinor allele predicts treatment success. bMinor allele predicts treatment failure. cSNPs currently used in genotyping to decide treatment for CHC. %, Percentage of SNPs in major ethnic groups. CEU, European; CHI, Han Chinese; YRI, Yorubi Africans. SNP frequencies are from the 1000 Genome Project pilot genotyping data.