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Table 1 Multivariate analysis of hepatic OATP expression in relation to 10 non-genetic factors in the total sample set of 143 human livers

From: Genetics is a major determinant of expression of the human hepatic uptake transporter OATP1B1, but not of OATP1B3 and OATP2B1

  P-value
Non-genetic factor SLCO1B1mRNA OATP1B1 protein SLCO1B3mRNA OATP1B3 protein SLCO2B1mRNA OATP2B1 protein
Sex 0.903 0.766 0.661 0.463 0.623 0.072
Age 0.502 0.630 0.466 0.060 0.711 0.947
Smoking habit 0.534 0.454 0.173 0.731 0.214 0.278
Alcohol consumption 0.037 0.124 0.076 0.904 0.001 0.206
Pre-surgery drugs 0.294 0.786 0.638 0.401 0.567 0.168
Diagnosis 0.458 0.046 0.238 0.101 0.506 0.066
Bilirubin 0.846 0.108 0.348 0.194 0.997 0.847
γ-Glutamyl transferase 0.363 0.820 0.548 0.448 0.461 0.547
Cholestasis 0.286 0.020 0.008 0.021 0.467 0.232
C-reactive protein 0.039 0.070 0.873 0.132 0.520 0.466