From: Identification and MS-assisted interpretation of genetically influenced NMR signals in human plasma
Locus | SNP | CHR^{a} | POS^{a} | A^{a} | B^{a} | MAF | Chemical shift(ppm) | n | Beta'^{b} | P value | Chemical shifts for ratios (ppm) | n | Beta' ratios^{b} | P value ratios | P gain^{c} |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
GCKR | rs780094 | 2 | 27,594,741 | T | C | 41.4% | 1.370 | 1,688 | 0.0413 | 1.2x10^{-10} | 3.286/1.370 | 1,667 | -0.0407 | 2.8x10^{-15} | 4.3x10^{4} |
CPS1 | rs2216405 | 2 | 211,325,139 | C | T | 19.3% | 3.599 | 1,719 | 0.0456 | 4.5x10^{-14} | 3.599/2.475 | 1,718 | 0.0459 | 1.8x10^{-19} | 2.5x10^{5} |
PYROXD2 | rs4488133 | 10 | 100,149,126 | A | T | 34.3% | 2.757 | 1,735 | -0.0190 | 7.3x10^{-12} | 2.757/2.755 | 1,734 | -0.0123 | 2.9x10^{-94} | 2.5x10^{82} |
FADS1 | rs174547 | 11 | 61,327,359 | C | T | 30.0% | 2.801 | 1,733 | -0.0408 | 4.0x10^{-35} | 2.801/2.017 | 1,724 | -0.0449 | 1.1x10^{-94} | 3.8x10^{59} |
APOA1 | rs3741298 | 11 | 116,162,771 | C | T | 21.4% | 2.038 | 1,724 | 0.0363 | 8.4x10^{-11} | 4.162/4.082 | 1,715 | -0.0138 | 1.8x10^{-14} | 4.6x10^{3} |
LIPC | rs4775041 | 15 | 56,461,987 | C | G | 28.5% | 1.283 | 1,671 | 0.0320 | 1.4x10^{-10} | 1.068/1.029 | 1,664 | -0.0056 | 3.6x10^{-21} | 4.0x10^{10} |
CETP | rs247617 | 16 | 55,548,217 | A | C | 31.3% | 3.259 | 1,705 | 0.0529 | 7.6x10^{-15} | 2.211/2.011 | 1,695 | -0.0124 | 1.1x10^{-18} | 6.8x10^{3} |