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Figure 3 | Genome Medicine

Figure 3

From: Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma

Figure 3

Unsupervised analysis of the top 1,000 MVPs in formalin-fixed, paraffin wax-embedded (FFPE) human papillomavirus-positive (HPV+) and HPV-negative (HPV-) tumor samples. (A) Consensus clustering identified four sub-groups in HPV+ and HPV- groups, revealing sub-group 1a as candidate CIMP within the HPV+ group. (B) Clusters inferred by the unsupervised consensus-clustering algorithm for the top 1,000 MVPs as found using the MAD estimator.

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