Table 1 Three types of biomarkers for use in clinical studies
From: Proteomics: improving biomarker translation to modern medicine?
Biomarker type | Requirement |
|---|---|
Exploratory biomarkers | Evidence for scientific proof of concept |
Probable valid biomarkers | Measurement in an established analytical test system and evidence explaining the clinical significance of the results |
Known valid biomarkers | Biomarker test results should be accurately replicated at different sites, laboratories or agencies in cross-validation experiments |