|
Method
|
Estimates individual cancer profiles
|
Uses unmatched normal tissues
|
Requires minimal additional data
|
Tested on clinical data
|
|---|
|
ISOpure
|
Yes
|
Yes
|
Yes
|
Yes
|
|
ISOLATE [14]
|
No
|
NA
|
Yes
|
No
|
|
Erkkila [28]
|
No
|
NA
|
Yes
|
No
|
|
Lahdeskmaki [27]
|
No
|
NA
|
Yes
|
No
|
|
Venet [26]
|
No
|
NA
|
Yes
|
No
|
|
Tolliver [31]
|
No
|
NA
|
Yes
|
No
|
|
Ghosh [29]
|
No
|
Yes
|
No
|
No
|
|
Shen-Orr [30]
|
No
|
NA
|
No
|
No
|
|
Bar-Joseph [32]
|
No
|
NA
|
No
|
No
|
|
Wang [21]
|
No
|
NA
|
No
|
No
|
|
Stuart [20]
|
No
|
NA
|
No
|
No
|
|
Gosink [34]
|
Yes
|
No
|
Yes
|
No
|
|
Clarke [33]
|
Yes
|
No
|
Yes
|
No
|
- aMethods require minimal additional data if they do not require mixing proportions of normal and cancer cells for each input tumor sample for deconvolution.
- bNA, not applicable; No, negative assessment; Yes, positive assessment.
