Genes and pathways underlying regional and cell type changes in Alzheimer's disease

Table 1 Summary of subject information

Category	Control	AD	P-value
Gender	11 M/5 F	9 M/8 F	0.37
Age	81.7 ± 6.9	77.3 ± 9.1	0.13
PMI	10.8 ± 6.8	11.2 ± 6.3	0.85
Plaques	0.58 ± 0.51	2.59 ± 0.51	6.0E-11
Braak	1.50 ± 0.52	5.33 ± 0.62	6.0E-14

Control and AD groups are controlled for gender, age at death (years), and PMI (postmortem interval in hours) as closely as possible, but there is a significant difference in plaque burden (0 to 3; 0 = none, 1 = sparse, 2 = moderate, and 3 = severe) and Braak stage (0 to 6) [13] between groups, as expected. Values are mean ± standard deviation. Gender indicates the number of subjects of each gender (M, male; F, female) per group.

ISSN: 1756-994X