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Table 2 Annotation for lists of differentially expressed genes

From: Genes and pathways underlying regional and cell type changes in Alzheimer's disease

Gene category EASE score
Down with AD (in CA1)  
  Synaptic transmission 6.18E-14
  Cell-cell signaling 7.88E-12
  CNS-specific functions 2.99E-05
  Potassium channel activity 6.46E-05
  Neurogenesis 1.35E-04
  cAMP-mediated signaling 5.99E-04
  Lipoprotein 1.30E-03
Up with AD (in CA1)  
  Response to stress 2.36E-05
  Cell-matrix adhesion 8.79E-04
  MAPKKK cascade 2.73E-03
  Polymorphism 2.95E-03
  Hs_TGF beta signaling pathway 5.25E-03
  Cell proliferation 1.14E-02
  Cell death 1.22E-02
Enriched in CA3 (in control)  
  Transport 2.16E-11
  Neurogenesis 1.85E-08
  CNS-specific functions 7.37E-08
  Synaptic transmission 7.27E-07
  Cell growth and/or maintenance 1.28E-05
  Cytoskeletal protein binding 2.80E-04
  Potassium transport 3.04E-04
  Cholesterol biosynthesis 4.70E-04
Enriched in CA1 (in control)  
  Signal transducer activity 3.42E-09
  Response to external stimulus 3.70E-07
  Metallothionein 9.74E-06
  Immune response 1.53E-05
  Cell-cell signaling 1.89E-05
  Cell motility 4.31E-05
  Homeostasis 9.97E-05
  Polymorphism 9.48E-03
  1. Significantly overrepresented gene ontology categories (EASE score <0.01) are presented for region- and disease-related lists of differentially expressed genes. Numerous other similar significant categories are not included to reduce redundancy. Complete lists of differentially expressed genes are presented in Additional file 2. CNS, central nervous system; TGF, transforming growth factor.