Figure 3
From: Estimating exome genotyping accuracy by comparing to data from large scale sequencing projects
Distance to the reference set for decreasing coverage and increasing error rate. A reduction of the raw sequence amount for a randomly chosen sample of 1KG project, NA06986, reduces the similarity to the reference set (green-blue circles) indicating decreasing genotyping accuracy. A similar effect is observed when simulated genotyping errors are added to the variant calls (red-yellow triangles). A decreasing similarity of the test samples results in divergent trajectories.