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Figure 6 | Genome Medicine

Figure 6

From: Serum acute phase reactants hallmark healthy individuals at risk for acetaminophen-induced liver injury

Figure 6

Box plots of gene expression changes after treatment of cultures of human hepatocytes with drugs labeled as no-, less- or most-DILI-concern. (A) Serum amyloid. (B) Sulfide quinone oxidoreductase. (C) Apolipoprotein C2. (D) Ceruloplasmin. Box blots marked with a star are statistically significant at P < 0.05. Cultures of human hepatocytes were treated with drugs labeled as either no- (n = 8), low- (n = 45) or most-DILI-concern (n = 39) for 2 and 24 h, respectively. A full list of drugs used is given in Additional file 6.

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Genome Medicine

ISSN: 1756-994X

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